TY - JOUR A1 - Bajaj, P A1 - Chowdhury, S K A1 - Yucha, R A1 - Kelly, E J A1 - Xiao, G T1 - Emerging Kidney Models to Investigate Metabolism, Transport, and Toxicity of Drugs and Xenobiotics. Y1 - 2018/11/ N1 - R835738C002 N1 - R835738C001 JF - DRUG METABOLISM AND DISPOSITION J1 - DRUG METAB DISPOS VL - 46 IS - 11 SP - 1692 EP - 1702 ER - TY - JOUR A1 - Chang, S A1 - Weber, E J A1 - Van, N A1 - Eaton, D L A1 - Kelly, E J T1 - Liver and kidney on chips: micro-physiological models to understand transporter function. Y1 - 2016/11/ N1 - R835738C003 N1 - R835738C002 N1 - R835738C005 N1 - R835738 JF - CLINICAL PHARMACOLOGY & THERAPEUTICS VL - 100 IS - 5 SP - 464 EP - 478 ER - TY - JOUR A1 - Chang, S A1 - Weber, E J A1 - Sidorenko, V S A1 - Chapron, A A1 - Yeung, C K A1 - Gao, C A1 - Mao, Q A1 - Shen, D A1 - Wang, J A1 - Rosenquist, T A A1 - Dickman, K G A1 - Neumann, T A1 - Grollman, A P A1 - Kelly, E J A1 - Himmelfarb, J A1 - Eaton, D L T1 - Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity. Y1 - 2017/11/16 N1 - R835738C002 N1 - R835738 VL - 2 IS - 22 SP - 95978 (15 pp.) ER - TY - JOUR A1 - Chang, S-Y A1 - Voellinger, J L A1 - Van Ness, K P A1 - Chapron, B A1 - Shaffer, R M A1 - Neumann, T A1 - White, C C A1 - Kavanagh, T J A1 - Kelly, E J A1 - Eaton, D L T1 - Characterization of rat or human hepatocytes cultured in microphysiological systems (MPS) to identify hepatotoxicity. Y1 - 2017/04/ N1 - R835738C003 N1 - R835738C002 N1 - R835738 JF - TOXICOLOGY IN VITRO J1 - TOXICOL IN VITRO VL - 40 SP - 170 EP - 183 ER - TY - JOUR A1 - Monteiro, M B A1 - Ramm, S A1 - Chandrasekaran, V A1 - Boswell, S A A1 - Weber, E J A1 - Lidberg, K A A1 - Kelly, E J A1 - Vaidya, V S T1 - A High-Throughput Screen Identifies DYRK1A Inhibitor ID-8 that Stimulates Human Kidney Tubular Epithelial Cell Proliferation. Y1 - 2018/12/ N1 - R835738C002 N1 - R835738C001 JF - JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY J1 - J AM SOC NEPHROL VL - 29 IS - 12 SP - 2820 EP - 2833 ER - TY - JOUR A1 - Nolin, J D A1 - Lai, Y A1 - Ogden, H L A1 - Manicone, A M A1 - Murphy, R C A1 - An, D A1 - Frevert, C W A1 - Ghomashchi, F A1 - Naika, G S A1 - Gelb, M H A1 - Gauvreau, G M A1 - Piliponsky, A M A1 - Altemeier, W A A1 - Hallstrand, T S T1 - Secreted PLA2 group X orchestrates innate and adaptive immune responses to inhaled allergen. Y1 - 2017/11/2 N1 - R835738C002 N1 - R835738 N1 - R835738C001 VL - 2 IS - 21 SP - e94929 (18 pp.) ER - TY - JOUR A1 - Sakolish, C A1 - Weber, E J A1 - Kelly, E J A1 - Hummelfarb, J A1 - Mouneimne, R A1 - Grimm, F A A1 - House, J S A1 - Wade, T A1 - Chiu, W A A1 - Rusyn, I T1 - Technology Transfer of the Microphysiological Systems: A Case Study of the Human Proximal Tubule Tissue Chip. Y1 - 2018/09/ N1 - R835738C002 N1 - R835738C001 JF - SCIENTIFIC REPORTS J1 - Scientific Reports ER - TY - JOUR A1 - Scoville, D K A1 - Botta, D A1 - Galdanes, K A1 - Schmuck, S C A1 - White, C C A1 - Stapleton, P L A1 - Bammler, T K A1 - MacDonald, J W A1 - Altemeier, W A A1 - Hernandez, M A1 - Kleeberger, S R A1 - Chen, L C A1 - Gordon, T A1 - Kavanagh, T J T1 - Genetic determinants of susceptibility to silver nanoparticle-induced acute lung inflammation in mice. Y1 - 2017/10/ N1 - R835738C002 N1 - R835738 N1 - R835738C001 VL - 31 IS - 10 SP - 4600 EP - 4611 ER - TY - JOUR A1 - Van Ness, K P A1 - Chang, S-Y A1 - Weber, E J A1 - Zumpano, D A1 - Eaton, D L A1 - Kelly, E J T1 - Microphysiological systems to assess nonclinical toxicity. Y1 - 2017/08/ N1 - R835738C002 N1 - R835738C004 N1 - R835738C005 N1 - R835738 N1 - R835738C001 VL - 73 IS - 1 SP - 14.18.1 EP - 14.18.28 ER - TY - JOUR A1 - Vernetti, L A A1 - Gough, A A1 - Baetz, N A1 - Blutt, S A1 - Broughman, J R A1 - Brown JA, A1 - Foulke-Abel, J A1 - Hasan, N A1 - In, J A1 - Kelly, E A1 - Kovbasnjuk, O A1 - Repper J, A1 - Senutovitch, N A1 - Stabb, J A1 - Yeung, C A1 - Zachos, N C A1 - Donowitz, M A1 - Estes M, A1 - Himmelfarb, J A1 - Truskey, G A1 - Wikswo, J P A1 - Taylor, D T1 - Functional coupling of human microphysiology systems: intestine, liver, kidney proximal tubule, blood-brain barrier and skeletal muscle. Y1 - 2017/02/8 N1 - R835736C004 N1 - R835736 N1 - R835738C002 N1 - R835738C005 VL - 7 SP - 42296 (14 pp.) ER - TY - JOUR A1 - Vernetti, L A1 - Gough, A A1 - Baetz, N A1 - Blutt, S A1 - Broughman, J R A1 - Brown, J A A1 - Foulke-Abel, J A1 - Hasan, N A1 - In, J A1 - Kelly, E A1 - Kovbasnjuk, O A1 - Repper, J A1 - Senutovitch, N A1 - Stabb, J A1 - Yeung, C A1 - Zachos, N C A1 - Donowitz, M A1 - Himmelfarb, J A1 - Truskey, G A1 - Wikswo, J P A1 - Taylor, D L T1 - Functional coupling of human microphysiology systems: intestine, liver, kidney proximal tubule, blood-brain barrier and skeletal muscle. Y1 - 2017/02/8 N1 - R835736C004 N1 - R835738C002 N1 - R835738 VL - 7 SP - 42296 (14 pp.) ER - TY - JOUR A1 - Vernetti, L A1 - Gough, A A1 - Baetz, N A1 - Blutt, S A1 - Broughman, J R A1 - Brown, J A A1 - Foulke-Abel, J A1 - Hasan, N A1 - In, J A1 - Kelly, E A1 - Kovbasnjuk, O A1 - Repper, J A1 - Senutovitch, N A1 - Stabb, J A1 - Yeung, C A1 - Zachos, N C A1 - Donowitz, M A1 - Himmelfarb, J A1 - Truskey, G A1 - Wikswo, J P A1 - Taylor, D T1 - Corrigendum: Functional coupling of human microphysiology systems: intestine, liver, kidney proximal tubule, blood-brain barrier and skeletal muscle. Y1 - 2017/03/16 N1 - R835738C002 N1 - R835738C005 N1 - R835738 JF - SCIENTIFIC REPORTS J1 - Scientific Reports VL - 7 SP - 44517 ER - TY - JOUR A1 - Weber, E J A1 - Chapron, A A1 - Chapron, B D A1 - Voellinger, J L A1 - Lidberg, K A A1 - Yeung, C K A1 - Wang, Z A1 - Yamaura, Y A1 - Hailey, D W A1 - Neumann, T A1 - Shen, D D A1 - Thummel, K E A1 - Muczynski, K A A1 - Himmelfarb, J A1 - Kelly, E J T1 - Development of a microphysiological model of human kidney proximal tubule function. Y1 - 2016/09/ N1 - R835738C002 N1 - R835738 JF - KIDNEY INTERNATIONAL J1 - KIDNEY INT VL - 90 IS - 3 SP - 627 EP - 637 ER - TY - JOUR A1 - Weber, E J A1 - Himmelfarb, J A1 - Kelly, E J T1 - Concise review: current and emerging biomarkers of nephrotoxicity. Y1 - 2017/06/ N1 - R835738C002 N1 - R835738 JF - CURRENT OPINION IN TOXICOLOGY VL - 4 SP - 16 EP - 21 ER - TY - JOUR T1 - Excretory Processes in Toxicology:Drug Transporters in Drug Development. N1 - R835738C002 ER - TY - JOUR T1 - Weber EJ, Lidberg KA, Wang L, Bammler TK, MacDonald JW, Li MJ, Redhair M, Atkins WM, Tran C, Hines KM, Herron J, Xu L, Monteiro MB, Ramm S, Vaidya V, Vaara M, Vaara T, Himmelfarb J, Kelly EJ. Human Kidney on a Chip Assessment of Polymyxin Antibiotic Nephrotoxicity. JCI Insight 2018;:3(24): e123673. N1 - R835738C002 VL - 3 IS - 24 SP - e123673 ER -